发明名称 Aqueous compositions comprising arbekacin
摘要 The invention provides aqueous liquid pharmaceutical compositions comprising arbekacin and chloride ions. The compositions are well tolerable for use in a method for treatment or prevention of a disease of the upper or lower respiratory tract, wherein the composition is aerosolized and inhaled by the patient. Furthermore, the invention provides arbekacin hydrochloride.
申请公布号 US9511143(B2) 申请公布日期 2016.12.06
申请号 US201214344487 申请日期 2012.08.03
申请人 Meiji Seika Pharma Co., Ltd.;PARI Pharma GmbH 发明人 Keller Manfred;Yagi Yukihiro;Tanaka Masashi;Sugano Toshie;Shoji Kuniko;Sano Nao;Hahn Michael;Egle Roman
分类号 A61K31/7036;C07H15/234;A61K47/02;A61K9/00;A61K47/24;A61K9/19 主分类号 A61K31/7036
代理机构 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. 代理人 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Corless, Esq. Peter F.;Clarke Daniel W.
主权项 1. An aqueous liquid pharmaceutical composition comprising arbekacin and chloride ions, wherein the concentration of arbekacin, calculated as free base, is at least 100 mg/ml and the ratio of the molar amount of chloride ions to the molar amount of arbekacin is at least 0.9 : 1.
地址 Tokyo JP