发明名称 |
Aqueous compositions comprising arbekacin |
摘要 |
The invention provides aqueous liquid pharmaceutical compositions comprising arbekacin and chloride ions. The compositions are well tolerable for use in a method for treatment or prevention of a disease of the upper or lower respiratory tract, wherein the composition is aerosolized and inhaled by the patient. Furthermore, the invention provides arbekacin hydrochloride. |
申请公布号 |
US9511143(B2) |
申请公布日期 |
2016.12.06 |
申请号 |
US201214344487 |
申请日期 |
2012.08.03 |
申请人 |
Meiji Seika Pharma Co., Ltd.;PARI Pharma GmbH |
发明人 |
Keller Manfred;Yagi Yukihiro;Tanaka Masashi;Sugano Toshie;Shoji Kuniko;Sano Nao;Hahn Michael;Egle Roman |
分类号 |
A61K31/7036;C07H15/234;A61K47/02;A61K9/00;A61K47/24;A61K9/19 |
主分类号 |
A61K31/7036 |
代理机构 |
Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. |
代理人 |
Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Corless, Esq. Peter F.;Clarke Daniel W. |
主权项 |
1. An aqueous liquid pharmaceutical composition comprising arbekacin and chloride ions, wherein the concentration of arbekacin, calculated as free base, is at least 100 mg/ml and the ratio of the molar amount of chloride ions to the molar amount of arbekacin is at least 0.9 : 1. |
地址 |
Tokyo JP |