Device and method for concentrating and detecting magnetically marked cells in laminarly flowing media

摘要

The embodiments relate to a device and to a method for concentrating and detecting cells in flowing media, in particular magnetically marked cells in complex media such as blood. For this purpose, at least one magnet is used, said magnet being coupled to at least one magnetoresistance. In the method the cells are concentrated on a magnetoresistor by the least one external magnetic field having a pulsed operation.

主权项

1. A method, comprising:
concentrating and detecting magnetically marked cells in a laminarly flowing medium, wherein the magnetically marked cells are concentrated on a magnetoresistor by a gradient of at least a first external magnetic field having a first amplitude, wherein the magnetically marked cells are detected in a gradient of at least a second external magnetic field having a second amplitude, wherein the first amplitude is larger than the second amplitude, wherein the first external magnetic field is perpendicular to the second external magnetic field, and wherein the first external magnetic field is switched off in each measuring time interval during which the second external magnetic field is switched on.