| 发明名称 |
DRUG DELIVERY DEVICES AND GROWTH FACTOR FORMULATIONS FOR ACCELERATED WOUND HEALING |
| 摘要 |
The present invention is directed to novel drug delivery devices and pharmaceutical compositions containing growth and differentiation factor proteins. Said devices and compositions are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. The invention is especially useful for the supportive therapy of diabetic wounds and ulcers. |
| 申请公布号 |
US2016317666(A1) |
申请公布日期 |
2016.11.03 |
| 申请号 |
US201615089862 |
申请日期 |
2016.04.04 |
| 申请人 |
Biopharm Gesellschaft zur biotechnologischen Entwicklung von Pharmaka mbH |
发明人 |
PLOEGER Frank |
| 分类号 |
A61K47/26;A61K38/18 |
主分类号 |
A61K47/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preventing the binding of GDF-5 related proteins in solution to amorphous thermoplastic polymers, biodegradable materials or polyvinylpyrrolidon, comprising adding an amount of trehalose, dextran sulfate, carboxymethyldextran or carboxymethyldextran sulfate, sufficient to prevent said binding of said GDF-5 related proteins. |
| 地址 |
Heidelberg DE |
