发明名称 |
Methods of treating hepatitis |
摘要 |
The present invention relates to a method of treating hepatitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient. |
申请公布号 |
US9522163(B2) |
申请公布日期 |
2016.12.20 |
申请号 |
US201314094140 |
申请日期 |
2013.12.02 |
申请人 |
University of Pittsburgh—Of the Commonwealth System of Higher Education;Yale University |
发明人 |
Otterbein Leo E.;Choi Augustine M. K.;Zuckerbraun Brian Scott |
分类号 |
A61K33/00;A61P1/16;A61K45/06 |
主分类号 |
A61K33/00 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A method of treating hepatitis in a patient at risk of acute liver failure, comprising:
identifying a patient diagnosed as suffering from hepatitis that is not a post-operative result of liver transplantation, and who is at risk of acute liver failure; and administering to the patient by inhalation a gaseous pharmaceutical composition comprising from 100 ppm to 800 ppm of carbon monoxide for up to six hours per day to reduce hepatocyte death in the patient. |
地址 |
Pittsburgh PA US |