Diazole and triazole derivatives, processes for their preparation and anti-microbial compositions containing them.

摘要

Compoundsofformula(1):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="31" wi="79" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein:
<UnorderedLists id="ula01" listStyle="none"><ListItem>Q represents a -CH- group or a nitrogen atom; R<Sup>1</Sup> represents a methyiene group, a group of formula
<Chemistry id="chema02" num="0002"><Image id="ia02" he="6" wi="34" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry></ListItem><ListItem>(R<Sup>3</Sup> being a substituted or unsubstituted phenyl group) or a group of formula
<Chemistry id="chema03" num="0003"><Image id="ia03" he="7" wi="37" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry></ListItem><ListItem>(n being 1 or 2 and R<Sup>4</Sup> being a substituted or unsubstituted phenyl or phenylalkyl group); and A represents a group of formula -OR<Sup>2</Sup></ListItem><ListItem>(R<Sup>2</Sup> being an alkenyl group, an alkynyl group or a substituted or unsubstituted alkyl or phenyl group) or a group of formula
<Chemistry id="chema04" num="0004"><Image id="ia04" he="8" wi="36" file="IMGA0004.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry></ListItem><ListItem>(X being an oxygen or sulphur atom and R<Sup>11</Sup> being an aryl or aralkyl group or, when X represents an oxygen atom, R<Sup>11</Sup> being a hydrogen atom or a carbonyloxy or sulphonyioxy group) and</ListItem></UnorderedLists>

acid addition salts and metal complexes thereof are valuable antimicrobial agents having low toxicity to humans and other animals and are especially valuable for the eradication of fungi. Processes for preparing these compounds and antimicrobial compositions containing them are also provided.