| 发明名称 |
ANTITUMOR COMPOSITIONS |
| 摘要 |
Organic acid addition salts of the antitumor agent 4 min -(9-acridinylamino)methanesulfon-m-anisidide(m-AMSA) are made substantially more water-soluble by addition of nicotinamide. Solid dosage form compositions provided by the present invention permit intravenous administration of m-AMSA without the necessity of employing an undesirable non-aqueous vehicle such as dimethylacetamide. |
| 申请公布号 |
ZA8103866(B) |
申请公布日期 |
1982.06.30 |
| 申请号 |
ZA19810003866 |
申请日期 |
1981.06.09 |
| 申请人 |
BRISTOL MYERS CO |
发明人 |
KAPLAN MURRAY ARTHUR;GRANATEK ALPHONSE PETER;SHINAL EDWARD CHARLES |
| 分类号 |
A61K31/635;A61K31/00;A61K31/4406;A61K31/455;A61K47/12;A61K47/22;A61K47/26;A61P35/00;A61P35/02;C07D213/82;C07D219/10 |
主分类号 |
A61K31/635 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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