摘要 |
Compounds of formula I <IMAGE> in which R1 represents hydrogen, halogen, C1-C4alkyl or C1-C4alkoxy, R2 represents hydrogen, halogen, C1-C4alkyl, C1-C4alkoxy or a group of formula <IMAGE> wherein A represents oxygen, sulphur, carbonyl or a direct bond and R8 and R9, independently, represent hydrogen, halogen, C1-C4alkyl or C1-C4alkoxy R3 represents hydrogen or C1-C4alkyl, n is 0, 1 or 2, R4 represents C4-C24alkyl, R5 represents hydrogen, C1-C24alkyl or a group physiologically degradable to a hydrogen atom and R6 and R7 represent, independently, hydrogen, C1-C24alkyl, a group of formula <IMAGE> wherein B represents C1-C6alkylene and R10 and R11 represent, independently, hydrogen, halogen, C1-C4alkyl or C1-C4alkoxy; or a group physiologically degradable to a hydrogen atom; and the nitrogen containing groups are in meta- or para-position to each other and pharmaceutically acceptable acid addition salts thereof. The compounds are indicated for use in inhibiting hyperglycemia, for example in patients suffering from diabetes. |