| 摘要 |
<p>Propanone derivatives of the general formula (I) …<CHEM>… wherein A is a non-substituted aryl group or an aryl group substituted by a hydroxyl group, lower alkoxy group or halogen, or a non-substituted benzo(b)thienyl group or benzo(b)thienyl group substituted by a hydroxyl group, lower alkyl group, lower alkoxy group, an aryl group or halogen, B is a di- lower alkylamino group or heterocyclic group which contains at least one nitrogen atom and may be substituted by a lower alkyl group or an aralkyl group, but, when A is a p-methylphenyl group, B denotes a group other than a piperidino group, and R<1> is a hydrogen, lower alkyl group or an aryl group, and the pharmacologically allowable salts thereof are described. …<??>These derivatives are prepared by reaction of a compound of formula (II) with formaldehyde and a compound of formula (III) …<CHEM>… wherein A, R<1> and B have the same meaning as above. These compounds are useful for treating allergic diseases. Pharmaceutical compositions containing these compounds are also described.</p> |
