| 摘要 |
Acylated 2-benzimidazole derivatives of the formula <IMAGE> in which R denotes an optionally esterified or amidated carboxyl group or an optionally etherified or esterified hydroxymethyl group, R1 represents an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclic-aliphatic radical, R2 represents hydrogen or an aliphatic radical, and Ph represents a 1,2-phenylene group containing the radical R1-C(=O)-, have antiallergic properties and can be used as antiallergic pharmaceutical active compounds. They were prepared, for example, by reacting an appropriate 1,2-phenylenediamine, which is substituted by the acyl radical of the formula R1-C(=O) and can optionally also contain further substituents, or an acid addition salt thereof, e.g. its hydrochloride, with an acid of the formula R-COOH or a suitable reactive derivative thereof.
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