| 摘要 |
PURPOSE:A safe analgesic containing arphamenine A or B or its salt as an active ingredient. CONSTITUTION:An analgesic containing a compound shown by the formula (R is H or OH) or its salt as an active ingredient. The compound shown by the formula is an active substance for inhibiting aminopeptidase B produced by a bacterium such as Chromobacterium violaceum BMG 361-CH4 (FERM-P 6521), etc. The form of dosage is any of oral administration, injection, and rectal suppository. A dose is 0.02-200mg/time/person, administered once daily. This substance enhances analgesic action of morphine, is a novel strong analgesic itself completely different from morphine.
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