METHOD OF ACCELERATING THE DISSOLUTION OF A HARD- SOLUBLE LYOPHILIZED MEDICAMENT USING A MAGNETIC STIRRER

摘要

In a method of accelerating the dissolution of hard-soluble lyophilized medicaments based on proteins, a magnetic body is introduced into an end container under sterile conditions prior to the lyophilization of the batch. The end container is brought into the region of a magnetic rotary field after addition of a solvent to the lyophilized batch, whereupon the magnetic body is set in motion. An arrangement for carrying out the method includes a heatable block of antimagnetic material with one or more accommodation openings for the end containers. A rotating magnetic stirrer is installed below the accommodation openings.