发明名称 |
ANTIPSYKOTISKA 1-FLUORFENYLBUTYL-4-( 2-PYRIMIDINYL) PIPERAZINDERIVAT. |
摘要 |
Disubstituted N,N-piperazinyl derivatives are disclosed wherein one substituent is a pyrimidin-2-yl ring and the other is a 4 carbon chain attached to a p-fluorophenyl ring at the terminal carbon. The terminal carbon of this butylene chain is also bonded to an oxygen atom as part of a carbonyl, carbinol, or ketal functionality. These compounds possess psychotropic properties, particularly atypical antipsychotic activity of good duration. By virtue of pre-clinical pharmacological testing, these compounds appear useful as potential antipsychotic agents which lack the typical movement disorder side-effects of standard antipsychotic agents. |
申请公布号 |
FI850850(A0) |
申请公布日期 |
1985.03.01 |
申请号 |
FI19850000850 |
申请日期 |
1985.03.01 |
申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
YEVICH, JOSEPH P.;LOBECK, JR., WALTER G. |
分类号 |
C07D239/42;A61K;A61K31/505;A61P25/18;C07D;C07D239/00;C07D239/47;C07D317/00;C07D317/12;C07D403/04;C07D405/12 |
主分类号 |
C07D239/42 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|