PROCESS OF PRODUCING PHARMACEUTICAL COMPOSITION OF FAMOTIDINE FOR INJECTION

摘要

By the addition of L-aspartic acid, the solubility of Famotidine in water can be effectively improved for providing a stable aqueous solution of Famotidine for injection. A lyophilized composition of Famotidine for injection is also prepared by lyophilizing an aqueous solution containing Famotidine together with L-aspartic acid and/or L-glutamic acid. Mannitol may be also added to the aqueous solution. as an excipient.