2'-SUBSTITUTED-SPIRO[BENZOFURAN-2(3H),1'- CYCLOALKANES]AND INTERMEDIATES THEREOF, A PROCESS FOR PREPARING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AND THEIR USE AS MEDICAMENTS

摘要

of the disclosure: 2'-Substituted-spiro/benzofuran-2(3H), 1` - cycloalkanes! and methods of preparing same are described. On the aromatic portion of the benzofuran ring, there may Le a substituent or substituents including halogen, amino,lower-alkyl-substituent amino, lower alkyl, lower alkoxy hydroxy and nitro. The substituents at the 2-position of the cyclohexane ring are -(CH2) nNR1R2 where n is o, 1 or Z and R1 and R1 and R2 are each independently hydrogen and alkyl of 1-3 carbons. These compounds are useful as antidepressants and analgesics. Various other compounds which are useful as intermediates for preparing the aforementioned compounds and methods for preparing same are also described.