发明名称 |
METHOD FOR THE TREATMENT OF MALIGNANCIES |
摘要 |
The present invention provides for the intratumoral delivery of at least one immunostimulatory cytokine in combination with at least one checkpoint inhibitor. In particular, it provides delivery of a plasmid encoding the immunostimulatory cytokine using intratumoral electroporation. The checkpoint inhibitor may be administered systemically or encoded on a plasmid and delivered using intratumoral electroporation. The checkpoint inhibitor may be delivered contemporaneously with or after treatment with the immunomodulatory cytokine. |
申请公布号 |
WO2016154473(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
WO2016US24079 |
申请日期 |
2016.03.24 |
申请人 |
ONCOSEC MEDICAL INCORPORATED;PIERCE, Robert, H.;DAUD, Adil |
发明人 |
PIERCE, Robert, H.;DAUD, Adil |
分类号 |
C12N15/09;A61K38/20;A61N1/32;C12N15/63;C12N15/66;C12P19/34 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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