| 摘要 |
PURPOSE:To selectively remove LDL and VLDL, by converting at least a part of a porous cellulose gel having a specific range of an exclusion limit MW contacted with a liquid to sulfuric ester to form an adsorbent for lipoprotein. CONSTITUTION:A porous cellulose gel, o which the exclusion limit MW measured by using spherical protein is one million - one billion, is coupled by sulfuric acid and carbondiimide in a solvent such as dimethylformamide to convert at least a part of the porous cellulose gel contacted with a liquid to sulfuric ester. As the porous structure of the porous cellulose gel, a full porous one is more suitable than a surface porous one and it is pref. that a void volume is 20% or more. The shape if a carrier can be selected from an arbitrary shape and, when a granular carrier is used, the particle size thereof is desirably 1-5,000mum.
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