| 摘要 |
Methods for treating hydrocephalus using a shunt, the shunt having one or more CSF intake openings in a distal portion, a valve disposed in a proximal portion of the shunt, and a lumen extending between the one or more CSF intake openings and the valve, the method comprises deploying the shunt in a body of a patient so that the distal portion of the shunt is at least partially disposed within a CP angle cistern, a body of the shunt is at least partially disposed within an IPS of the patient, and the proximal portion of the shunt is at least partially disposed within or proximate to a JV of the patient, wherein, after deployment of the shunt, CSF flows from the CP angle cistern to the JV via the shunt lumen at a flow rate in a range of 5 ml per hour to 15 ml per hour. |
| 主权项 |
1. A system for treating hydrocephalus, including normal pressure hydrocephalus, and/or elevated intracranial pressure, the system comprising:
a shunt configured for being deployed in an inferior petrosal sinus (IPS) of a patient, the shunt comprising
a distal portion configured for being introduced into and secured within a cerebellopontine (CP) angle cistern of the patient via the IPS, the CP angle cistern containing cerebrospinal fluid (CSF), the distal portion including one or more CSF intake openingsa proximal portion configured for being secured within or proximate to a jugular vein (JV) of the patient, anda body portion extending from the distal portion to the proximal portion, the body portion comprising a lumen in communication with the one or more CSF intake openings in the distal portion, and with a valve disposed within or otherwise coupled to the proximal portion, such that, when the shunt is deployed in the IPS with the distal portion of the shunt secured within the CP angle cistern and the proximal portion of the shunt secured within or proximate to the JV, CSF flows from the CP angle cistern into the JV through the one or more CSF intake openings, shunt lumen, and valve, respectively, to maintain a normal pressure differential between the subarachnoid space and venous system of the patient; a tissue penetrating member; and a delivery system configured to introduce the shunt and tissue penetrating member into the patient's body through a femoral vein access point, and to navigate the shunt and tissue penetrating member in the patient's body through the JV and into the IPS. |
