DIAGNOSTIC PROCEDURES USING RADIO LABELED SUCRALFATE AND DERIVATIVES OR PRECURSORS THEREOF

摘要

DIAGNOSTIC PROCEDURES USING RADIO LABELED SUCRALFATE AND DERIVATIVES OR PRECURSORS THEREOF A novel diagnostic procedure for the in vivo clinical evaluation of gastrointestinal ulcer disease and other diseases associated with loss of mucosal integrity in humans which comprises the oral administration of an effective amount of radiolabeled sucralfate or derivative or precursor thereof to the human host, followed by scintigraphic imaging of the gastrointestinal area of interest with scintigraphic imaging equipment. A novel radiopharmaceutical composition comprising an aqueous solution or suspension containing an amount of a radiolabeled sucralfate or derivative or precursor thereof effective for invivo scintigraphic imaging of the gastrointestinal or other muscosal areas in humans.