发明名称 |
A CYTOTOXIC PROTEIN |
摘要 |
A cytotoxic protein expressed by human peripheral blood mononuclear cells is isolated in essentially homogenous form. This protein may be used to elicit production of polyclonal or monoclonal anti-cytotoxin antibodies. Hybridomas secreting anti-cytotoxin antibodies are identified by a solid phase bioassay. The antibodies are useful in the immunopurification of cytotoxins. The purified cytotoxic proteins are useful for the treatment of virus-infected or tumor target cells, either alone or in combination with interferon or a metabolic blocker. |
申请公布号 |
ZA8509757(B) |
申请公布日期 |
1986.09.24 |
申请号 |
ZA19850009757 |
申请日期 |
1985.12.20 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED |
发明人 |
DAVID WALLACH |
分类号 |
G01N33/53;A61K35/12;A61K35/14;A61K38/16;A61K38/21;A61K38/36;A61K39/00;A61K39/395;C07K1/22;C07K14/005;C07K14/195;C07K14/47;C07K14/52;C07K16/00;C07K16/18;C07K16/24;C12N5/00;C12N5/10;C12N5/20;C12N15/02;C12P21/00;C12P21/08;C12R1/91;G01N33/569;G01N33/577 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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