| 摘要 |
Herein disclosed are aminopyrimidine derivatives having the formula …<CHEM>… or tautomeric form thereof, wherein R is halogen or lower alkyl containing 1 to 3 carbon atoms; R<1> is hydrogen, hydroxy, cyclopropyl, pyridinyl, 1-methyl-1H-pyrrol-2-yl, 2-furanyl, phenyl; and n is an integer from 1 to 3, providing that when R<1> is hydroxy n is 2 or 3, and the pharmaceutically acceptable addition salts thereof. Also disclosed are processes for their preparation and methods of using the derivatives and aceutical compositions. The derivatives are useful for increasing cardiac contractility in a mammal. |
