| 摘要 |
Guanidinothiazole compds. (I), useful as medicaments, esp. a gastric secretion inhibitor, are prepd. by the reaction of II and III. Thus, the mixture of 16.8g amidinothiourea and 75ml aceton is reacted with 18g 1,3-dichloroaceton to give 26.53g 2-guanidino -4- chloromethylthiazolyhydrochloride (m.p.=191-193 deg. c).
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