摘要 |
PURPOSE:The titled pharmaceutical containing a human blood serum albumin or glycine and, as necessary, a buffer agent. CONSTITUTION:A stable growth hormone releasing factor (GRF) pharmaceutical obtained by adding 100mug-30mg, based on 100mug GRF (a peptide expressed by the formula), human blood serum albumin or glycine as a stabilizer to the GRF and further adding a buffer agent, e.g. acetate, phosphate, citrate, etc., as necessary, to give 2-7pH, preferably 2.5-5pH for providing a stabler pharmaceutical. The dosage form may be either one of solution of solid form, but is preferably the form of freeze-dried product as a medicine stable for a long period. In this case, nitrogen is more preferably sealed after freeze-drying. Furthermore, the pharmaceutical is readily dissolved by adding a suitable dissolvent solution in use and particularly useful as a simple freeze-dried injection of the type soluble in use.
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