| 摘要 |
PURPOSE:To improve the productivity of L-threonine or L-isoleucine, by culturing a microbial strain belonging to Corynebacterium genus, etc., in a medium and producing L-threonine or L-isoleucine in the medium. CONSTITUTION:L-threonine or L-isoleucine is produced and accumulated in a medium by culturing a microbial strain belonging to Corynebacterium genus or Brevibacterium genus having a recombinant DNA of a vector DNA and a DNA fragment carrying a genetic information participating in the synthesis of homoserine dehydrogenase and homoserine kinase of a microorganism belonging to Corynebacterium genus or Brevibacterium genus. The produced amino acid is separated from the culture product. |
