Phenyl alkyl carbamate compounds for use in preventing or treating epilepsy or epilepsy-related syndrome

摘要

The present invention provides a pharmaceutical composition for preventing and/or treating a epilepsy or epilepsy-related syndrome, for example an intractable epilepsy or its related syndrome such as drug-resistant epilepsy, comprising the phenyl alkyl carbamate compound as an active ingredient, and a use of the phenyl alkyl carbamate compound for preventing and/or treating epilepsy or epilepsy-related syndrome.

主权项

1. A method for treating an epilepsy or an epilepsy-related syndrome in a subject in need thereof comprising administering to the subject a pharmaceutically effective amount of a pharmaceutical composition comprising a compound represented by the following Chemical Formula I or a pharmaceutically acceptable salt thereof, as an active ingredient: wherein, X is a halogen, n means the number of substituent X and is an integer from 1 to 5, wherein X is the same or different from each other, when n is 2 or larger, R1 is a linear or branched C1-C4 alkyl group, A is selected from the group consisting of an allyl, a C1-C19 linear or branched alkyl group, a C2-C8 alkoxy alky ether group and a carbamoyl derivative represented by B is selected from the group consisting of an allyl, a C1-C19 linear or branched alkyl group, a C2-C8 alkoxy alky ether group and a carbamoyl derivative represented by and and R2 and R3 may be the same as or different from each other, and independently selected from the group consisting of hydrogen, a linear or branched alkyl group of C1-C4, a cycloalkyl group of C3-C8, and benzyl group.