| 发明名称 |
Methods, Kits, and Compositions for Stem Cell Self-Renewal |
| 摘要 |
The present invention relates to methods and kits for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods, kits, and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population. |
| 申请公布号 |
US2016355784(A1) |
申请公布日期 |
2016.12.08 |
| 申请号 |
US201615156851 |
申请日期 |
2016.05.17 |
| 申请人 |
STOWERS INSTITUTE FOR MEDICAL RESEARCH |
发明人 |
Perry John M.;Li Linheng;Grindley Justin C. |
| 分类号 |
C12N5/0789;A61K35/28 |
主分类号 |
C12N5/0789 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An ex vivo method for expanding the number of hematopoietic stem cells (HSC) in a population of mononuclear cells (MNC) comprising culturing the population of MNCs comprising at least one HSC in an HSC expansion media for a period of time sufficient to expand the number of HSCs in the MNC population, wherein the expanded HSCs are functional with long term, multi-lineage, repopulating potential. |
| 地址 |
Kansas City MO US |
