| 摘要 |
PURPOSE:To efficiently produce pyruvic acid useful as a raw material for drugs and chemicals, by treating hydroxyacetone or methylglyoxal with an enzyme or a microorganism or an extract thereof. CONSTITUTION:An aqueous solution of hydroxyacetone or methylglyoxal containing a proper inorganic salt is treated with an enzyme such as alcohol oxidase, alcohol dehydrogenase, aldehyde oxidase, aldehyde hydrogenase, formaldehyde dehydrogenase, etc., a microorganism producing the enzyme or an extract thereof at pH4-9 at 4-40 deg.C by a method wherein the enzyme, etc., is directly dissolved or suspended or the enzyme, the microorganism or the extract is immobilized and the aqueous solution is directly brought into contact with the immobilized substance, the reaction is carried out and pyruvic acid is obtained from the reaction solution by organic solvent extraction method.
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