| 摘要 |
Aminoaryl- beta -sulphatoethylsulphone compounds, for example 4-( beta -sulphatoethylsulphonyl)-aniline, can be made simply and quickly from their corresponding beta -hydroxyethylsulphone compounds by sulphation. A solution, suspension or paste of an aminoaryl- beta -hydroxyethylsulphone compound or its acylamino compound in sulphuric acid or aqueous sulphuric acid is injected into a hot inert gas stream in a convection dryer, which results in simultaneous drying, esterification and hydrolysis of any acylamino groups present. The sulphated compound is obtained preferably in granule form. |
