| 发明名称 |
PROCESS FOR THE PREPARATION OF OLIGONUCLEOTIDS CONTAINING PHARMACEUTICALLY OR BIOTECHNOLOGICALLY USEFUL SARBOCYCLIC NUCLEOTID UNITS |
| 摘要 |
Novel oligonucleotides of formula (V) contg. carbocyclic units are prepd. by reactions between (II) and (III). Protective gps. formed during prepn. are finally removed from the oligo-nucleotide prod.. Y = thyminyl, cytosinyl, adenylyl or guaninyl; X = CH2 or O; n = 1-48; R = PO2H, PO2OC6H4Cl or P(OCH2CH2CN)N(R')2; R' = alkyl; A' = substd. alkyl chain (spacer). |
| 申请公布号 |
HU895368(D0) |
申请公布日期 |
1990.01.28 |
| 申请号 |
HU19890005368 |
申请日期 |
1989.10.20 |
| 申请人 |
MTA KOEZPONTI KEMIAI KUTATO INTEZETE,HU |
发明人 |
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| 分类号 |
A61K31/00;C07H21/00;C12N15/00 |
主分类号 |
A61K31/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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