发明名称 |
VECTORS AND COMPOUNDS FOR EXPRESSION OF ZYMOGEN FORMS OF HUMAN PROTEIN C |
摘要 |
A method for the recombinant production of zymogen forms of human protein C is described. These zymogen forms differ from native zymogen protein C in their increased sensitivity to activation by thrombin and thrombin/thrombomodulin. DNA compounds, vectors, and transformants useful in the method are also disclosed. |
申请公布号 |
ZA8809497(B) |
申请公布日期 |
1990.08.29 |
申请号 |
ZA19880009497 |
申请日期 |
1988.12.20 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
NILS ULRIK BANG;HARTMUT JOSEF EHRLICH;BRIAN WILLIAM GRINNELL;SAU-CHI BETTY YAN |
分类号 |
C12N9/50;A61K31/70;A61K38/43;A61K38/46;A61P7/04;C07H21/04;C07K14/00;C07K14/745;C07K19/00;C12N5/10;C12N9/64;C12N15/09;C12N15/12;C12N15/15;C12R1/91 |
主分类号 |
C12N9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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