发明名称 |
RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF PROTEINS |
摘要 |
Chelating compounds of specified structure are useful for radiolabeling targeting proteins such as antibodies. The radiolabeled antibodies, or catabolites thereof, demonstrate improved biodistribution properties, including reduced localization within the intestines. |
申请公布号 |
AU5956790(A) |
申请公布日期 |
1991.01.08 |
申请号 |
AU19900059567 |
申请日期 |
1990.06.15 |
申请人 |
NEORX CORPORATION |
发明人 |
LINDA M. GUSTAVSON;ANANTHACHARI SRINIVASAN;SUDHAKAR KASINA;ALAN R. FRITZBERG |
分类号 |
C07D307/18;A61K39/395;A61K51/00;A61K51/10;C07C323/60;C07D263/26;C07D309/08;C07D327/04;C07F13/00;C07K5/06;C07K14/705;C07K14/715;C07K16/00 |
主分类号 |
C07D307/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|