发明名称 |
A COMPOSITION COMPRISING (-)-TRANS-3-(5,6-DIHYDRO-4H-PYRROLO [3,2,1-IJ] QUINOLIN-1-YL)-4-(1H-INDOL-3-YL) PYRROLIDINE-2, 5-DIONE IN COMBINATION WITH A SECOND ANTI-PROLIFERATIVE AGENT |
摘要 |
The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or a pyrroloquinolinyl-pyrrolidine-2,5-dione compound in combination with a therapeutically effective amount of a second anti-proliferative agent. |
申请公布号 |
CA2752232(C) |
申请公布日期 |
2016.11.22 |
申请号 |
CA20102752232 |
申请日期 |
2010.02.11 |
申请人 |
ARQULE, INC.;KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
CHAN, THOMAS C. K.;FRANCE, DENNIS S.;ISHII, KENICHI;PUCCI, PAOLO |
分类号 |
A61K31/4745;A61K45/06;A61P35/00 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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