摘要 |
30,405-00 .DELTA.22-DERIVATIVES OF LL-F28249 COMPOUNDS The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cvaneoariseus subsp. noncvanoaenus having deposit accession number NRRL 15773. The derivatives of the present invention have the 23hydroxy group react to form a double bond in the 22,23 position. The novel derivatives of the present invention possess activity as anthelmintic, ectoparasitic, insecticidal, acaricidal and nematicidal agents. They also are useful in areas of human and animal health and in agricultural crops. |