发明名称 |
METHOD OF INDENTIFYING AND MODULATING THE ACTIVITY OF LABEL RETAINING CELLS FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES |
摘要 |
2106862 9217779 PCTABS00016 Methods of detecting label retaining cells in self-renewing tissues, such as hair follicle, are provided. Methods of modulating the activity of slow-cycling cells and methods of evaluating the efficacy of agents for modulating the activity of stem cell populations are also provided. Generally, cells are continuously labeled, induced into a proliferative phase by exposure to an agent such as TPA or a cytokine, and then observed in relation to established criteria.
|
申请公布号 |
CA2106862(A1) |
申请公布日期 |
1992.09.28 |
申请号 |
CA19922106862 |
申请日期 |
1992.03.20 |
申请人 |
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (THE);NEW YORK UNIVERSITY |
发明人 |
LAVKER, ROBERT M.;SUN, TUNG-TIEN;COTSARELIS, GEORGE |
分类号 |
C12Q1/02;C12N5/071;C12N5/074;G01N33/50;(IPC1-7):C12Q1/68;A61K49/02;G01N33/58 |
主分类号 |
C12Q1/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|