发明名称 USE OF INTERFERON AND SUBSTANCE HAVING ANTIMALARIAL ACTIVITY FOR TREATING MALARIA INFECTION
摘要 PURPOSE: To provide permanent healing of malaria in the erythrocytic phase, i.e., the clinical phase and prevent the relapse by using a combination of an interferon with a substance having the antimalarial activities. CONSTITUTION: A combination of an interferon, preferably interferon-γand a substance having antimalarial activities, e.g. 9-aminoacridines (e.g. mepacrine), 4-aminoquinolines (e.g. chloroquine), 8-aminoquinolines (e.g. primaquine), biguanides having dihydrofolate reductase inhibiting effects (e.g. cycloguanil), diaminopyrimidines (e.g. pyrimethamine), a quinine salt, a sulfonamide, a sulfanilamide, an antibiotic substance (e.g. tetracyline) and a sulfone is used for producing a pharmaceutical preparation for treating malaria infection in the erythrocytic clinical phase.
申请公布号 JPH04316522(A) 申请公布日期 1992.11.06
申请号 JP19910322721 申请日期 1991.12.06
申请人 BOEHRINGER INGELHEIM INTERNATL GMBH 发明人 URURITSUHI BIINTSURU
分类号 A61K31/10;A61K31/12;A61K31/135;A61K31/15;A61K31/155;A61K31/175;A61K31/18;A61K31/435;A61K31/47;A61K31/475;A61K31/49;A61K31/505;A61K31/535;A61K38/21;A61K45/06;A61P33/02;A61P43/00 主分类号 A61K31/10
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