PROCESS FOR THE PREPARATION OF VITAMIN A AND SOME OF ITS DERIVATIVES

摘要

According to this process a stereospecific reduction of the two hydroxyl groups of an etherdiol is carried out using a mixture (titanium trichloride, lithium aluminium hydride) at a temperature of approximately between 5 DEG C and 40 DEG C and the ether obtained is optionally converted into vitamin A, retinal or retinoic acid. Application to the synthesis of all-trans compound taken from the group consisting of vitamin A and its ethers, retinal and retinoic acid and their 13-cis isomers.