发明名称 2-AMINOPROPAN-1,3-DIOL CHEMOTHERAPEUTIC AGENTS
摘要 2120234 9308120 PCTABS00021 The present invention provides a pharmaceutical system adapted to inhibit the growth of a mammalian cancer tumor or cell characterized by a chemotherapeutic agent selected from adriamycin and cisplatin in conjunction with an effective amount of a potentiating agent comprising a compound having formula (I), wherein R is C5-C20 alkyl, alkenyl or alkynyl. The present invention further provides a method of inhibiting the in vitro growth of a mammalian cancer tumor or cell comprising administering to the tumor or cell an amount of a chemotherapy agent selected from adriamycin and cisplatin effective to inhibit growth of the tumor or cell; and administering to the tumor or cell an amount of a potentiating agent comprising a compound having formula (II) wherein R is C5-C20 alkyl, alkenyl or alkynyl, in an amount effective to induce enhanced growth inhibition produced by the chemotherapy agent.
申请公布号 CA2120234(A1) 申请公布日期 1993.04.29
申请号 CA19922120234 申请日期 1992.10.19
申请人 SPHINX PHARMA CORP 发明人 JIANG JACK B
分类号 A61K31/13;A61K31/28;A61K31/35;A61K33/24;A61P35/00;(IPC1-7):A61K33/24;A61K31/71 主分类号 A61K31/13
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