发明名称 |
WERKWIJZE VOOR HET BEREIDEN VAN EEN GENEESMIDDEL MET ANTIBACTERIELE WERKING EN WERKWIJZE VOOR HET BEREIDEN VAN GENEESKRACHTIGE OXADETHIA-CEFALOSPORINEDERIVATEN. |
摘要 |
<p>Antibacterial 7-substituted aminoacetamido oxadethiacephalosporins of the formula: <IMAGE> [wherein R is substituted amino, substituted phenyl, or 5- or 6-membered hetero ring; Ar is aryl; Y is hydrogen or methoxy; Het is 5- or 6-membered aromatic hetero ring; and Z is hydroxy or carboxy protecting group] preparable e.g. by acylation of 7 alpha -methoxy-7 beta -amino-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives, are highly active against gram-positive and gram-negative bacteria, especially those resistant to other cephalosporins and penicillins.</p> |
申请公布号 |
NL190267(C) |
申请公布日期 |
1994.01.03 |
申请号 |
NL19770009611 |
申请日期 |
1977.08.31 |
申请人 |
SHIONOGI & CO., LTD. TE OSAKA, JAPAN. |
发明人 |
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分类号 |
C07D505/06;A61K31/535;A61K31/5365;A61P31/00;A61P31/04;C07D501/36;C07D505/00;C07D505/20;C07D505/22;(IPC1-7):A61K31/545;C07D501/60 |
主分类号 |
C07D505/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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