COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES
摘要
Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof in an amount and formulation sufficient to inhibit or induce drug-sensitization in a parasite. The methods can comprise administering a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof to a parasite in an amount and formulation sufficient to inhibit or induce drug-sensitization in the parasite.
申请公布号
EP3107537(A1)
申请公布日期
2016.12.28
申请号
EP20150752397
申请日期
2015.02.19
申请人
The Texas A&M University System
发明人
SACCHETTINI, James, C.;MILLER, Matthew, W.;WALLIS, Deeann;ZHOU, Nian, E.;FOSSUM, Theresa, W.