SURFACE STABILIZATION OF BIOSENSORS

摘要

A sensor apparatus (such a chemFET, ion-sensitive FET, Ion Torrent Proton), including a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use, e.g., in nucleic acid sequencing. The semiconductor device can include a well and optionally a bead conjugated to a nucleic acid disposed in the well.