METHODS FOR IDENTIFYING COMPOUNDS THAT DIRECTLY BIND TO INSECT TRANSIENT RECEPTOR POTENTIAL CHANNELS
摘要
The present invention relates to a screening method for determining whether or not a candidate compound directly binds to an insect transient receptor potential V (TRPV) channel. The present invention further provides a method of identifying a compound that directly binds to a Nanchung protein, TRP and/or TRPV protein and/or channel using a binding assay. The present invention further provides a method of classifying an insecticide compound by its mode of action using the binding assay and/or a functional assays.
申请公布号
WO2016203014(A1)
申请公布日期
2016.12.22
申请号
WO2016EP64078
申请日期
2016.06.17
申请人
BASF SE
发明人
VON DEYN, Wolfgang;NESTEROV, Alexandre;KANDASAMY, Ramani;LONDON, Damian;SALGADO, Vincent L.;LELITO, Katherine