RECOMBINANT PLANTS AND MICROORGANISMS HAVING A REVERSE GLYOXYLATE SHUNT

摘要

Provided are microorganisms and plants that express or overexpress enzymes that catalyze the conversion of a four carbon metabolite (malate) to acetyl-CoA. Also provided are methods of generating such organisms and plants and methods of synthesizing biomass, biofuel, oil, chemicals and biochemicals using such organisms and plants.

主权项

1. A recombinant microorganism comprising a metabolic pathway for the synthesis of acetyl-CoA and isocitrate from a four-carbon substrate using a pathway comprising one or more polypeptides having malate thiokinase activity, malyl-CoA lyase activity and/or isocitrate lyase activity.