发明名称 MODULATION OF TRANSTHYRETIN EXPRESSION
摘要 Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof.
申请公布号 US2016369275(A1) 申请公布日期 2016.12.22
申请号 US201615190533 申请日期 2016.06.23
申请人 Ionis Pharmaceuticals, Inc. 发明人 Monia Brett P.;Freier Susan M.;Siwkowski Andrew M.;Guo Shuling
分类号 C12N15/113 主分类号 C12N15/113
代理机构 代理人
主权项
地址 Carlsbad CA US