| 摘要 |
The present invention relates to a fluidic device for in vitro complex living tissue reconstruction comprising at least one set of distinct compartments, which set comprises at least a first, second and a third compartment and a separating material separating the compartments comprised in the set of distinct compartments from one another, wherein the at least one set of distinct compartments defines at least one exchange region in which the compartments comprised in the set congregate and wherein at least a part of the separating comprised in the at least one exchange region is configured such that direct communication is allowed between each of the compartments comprised in the at least one set of distinct compartments with one another. The present invention also relates to the use of the fluidic device of the present invention. The present invention further relates to a perfusion system comprising the fluidic device and to a method for in vitro culturing and/or co-culturing, including complex living tissue reconstruction using the fluidic device and/or perfusion system of the present invention, as well as to a hollow membrane and use of the hollow membrane for culturing, co-culturing, evaluating, sampling and/or harvesting of cells, circulatory system cells, neuronal cells and/or interstitial cells, products and/or metabolites from the fluidic device of the present invention. |
