发明名称 |
TREATING INFECTION BY A PLATELET-TARGETING MICROBE USING NANOPARTICLES |
摘要 |
The present invention relates to prevention and/or treatment of infection by a platelet-targeting microbe in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating (and/or related uses) infection by a platelet-targeting microbe in a subject, using, inter alia, an effective amount of a nanoparticle comprising a) an inner core comprising a non-cellular material, b) an outer surface comprising a cellular membrane derived from a platelet; and optionally c) an agent for preventing said infection, treating said infection, diagnosing said infection, prognosing said infection and/or monitoring prevention or treatment of said infection. Exemplary platelet-targeting infections include infections by a bacterium, a virus, a fungus and/or a parasite. |
申请公布号 |
WO2016205009(A1) |
申请公布日期 |
2016.12.22 |
申请号 |
WO2016US36132 |
申请日期 |
2016.06.07 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ZHANG, Liangfang;HU, Che-Ming Jack;FANG, Ronnie H.;LUK, Brian T.;THAMPHIWATANA, Soracha Kun |
分类号 |
A61K9/14;A61K45/06;A61K45/08;A61K47/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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