| 发明名称 |
PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED SOLID DOSAGE FORM |
| 摘要 |
The present invention relates to a process for the production of an abuse-proofed solid dosage form containing at least one active ingredient with potential for abuse and a binder with a breaking strength of ≧500 N, by exposing a mixture comprising the active ingredient and the binder to ultrasound and force. |
| 申请公布号 |
US2016367501(A1) |
申请公布日期 |
2016.12.22 |
| 申请号 |
US201615249574 |
申请日期 |
2016.08.29 |
| 申请人 |
GRÜNENTHAL GMBH |
发明人 |
ARKENAU-MARIC Elisabeth;BARTHOLOMÄUS Johannes;KUGELMANN Heinrich |
| 分类号 |
A61K31/135;A61K47/10;A61K9/20;A61K9/00 |
主分类号 |
A61K31/135 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for the production of an abuse-proofed solid dosage form comprising at least one active ingredient with potential for abuse and at least one binder with a breaking strength of ≧500 N, wherein a mixture comprising the active ingredient and the binder is exposed to ultrasound and force. |
| 地址 |
Aachen DE |
