发明名称 |
NUCLEIC ACID MOLECULE, FUSION PROTEIN AND METHOD FOR ALTERING THE GENETIC MATERIAL OF A CELL |
摘要 |
The invention relates to a nucleic acid molecule encoding a fusion protein, said nucleic acid molecule comprising, in transcription direction 5´---3´, at least: one nucleic acid sequence encoding a DNA-binding domain; and a nucleic acid sequence encoding a FokI-type catalytic domain, the 3' end thereof comprising a nucleic acid sequence encoding a peptide comprising between 18 and 23 amino acids. The invention also relates to a fusion protein that can be obtained, for example, from the transcription of said molecule, and to a method for altering the genetic material of a cell using said molecule or protein. |
申请公布号 |
WO2016203088(A1) |
申请公布日期 |
2016.12.22 |
申请号 |
WO2016ES70459 |
申请日期 |
2016.06.17 |
申请人 |
BIOPRAXIS RESEARCH AIE;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS;FUNDACIÓ D'INVESTIGACIÓ SANITÀRIA DE LES ILLES BALEARS;UNIVERSIDAD DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA;UNIVERSIDAD DE BARCELONA |
发明人 |
GAINZA LAFUENTE, Eusebio Jesús;GAINZA LUCEA, Garazi;DEL POZO PEREZ, Angel;PASTOR NAVARRO, Marta;PEDRAZ MUÑOZ, José Luis;VIÑAS CIORDIA, Miguel;BACHILLER PEREZ, Daniel;GALVEZ JEREZ, Victor |
分类号 |
C12N9/22;C12N15/62;C12N15/90 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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