METHODS AND COMPOSITIONS USING LISTERIA FOR ADJUVANT TREATMENT OF CANCER
摘要
Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
申请公布号
EP2576791(B8)
申请公布日期
2016.12.21
申请号
EP20110787200
申请日期
2011.05.23
申请人
Aduro BioTech, Inc.
发明人
DUBENSKY, Thomas, W.;BROCKSTEDT, Dirk, G.;LEONG, Meredith;BAHJAT, Keith, S.