发明名称 PORPHYRIN DERIVATIVE AND PHOTOSENSITIZER CONTAINING THE SAME
摘要 PROBLEM TO BE SOLVED: To provide a porphyrin derivative capable of being specifically transferring into cancer cells by an oxygen reaction of a membrane protein specifically expressed in the cancer cells, a photosensitizer using characteristic of the porphyrin derivative to being specifically transferred into the cancer cells, a fluorescence visualization agent and MRI contrast medium.SOLUTION: There are provided a porphyrin derivative represented by the general formula (I) and a metal complex where metal ion are inserted into the porphyrin derivative. There is provided a metal complex where metal ions to be inserted are ions of Mn, Zn, Mg, Sn, Pt, Ag and Au and counter ions are Cl, Br, NO, CFSO, hydroxide ion or CHCOO. In the general formula (I), n is a natural number of 0 to 5 and R may be same or different.SELECTED DRAWING: None
申请公布号 JP2016155768(A) 申请公布日期 2016.09.01
申请号 JP20150033566 申请日期 2015.02.24
申请人 DOSHISHA 发明人 HITOMI YUTAKA;OHASHI NATSUMI
分类号 C07D487/22;A61K31/409;A61K49/00;A61P35/00 主分类号 C07D487/22
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