发明名称 グアニジン架橋を有する人工ヌクレオシドおよびオリゴヌクレオチド
摘要 An oligonucleotide or a pharmacologically acceptable salt thereof of the present invention contains a compound represented by formula I or II or a salt thereof, and at least one of nucleoside structures represented by formula I' or II' . According to the present invention, provided is a nucleic acid molecule for oligonucleotides having high binding affinity and specificity to a target nucleic acid, and exhibiting high nuclease resistance.
申请公布号 JP6048982(B2) 申请公布日期 2016.12.21
申请号 JP20140536921 申请日期 2013.09.19
申请人 国立大学法人大阪大学 发明人 小比賀 聡;壽 悠太朗;脇 玲子
分类号 C07H19/067;C07H19/167;C07H21/02;C12N15/09;C12N15/113 主分类号 C07H19/067
代理机构 代理人
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