发明名称 Enhanced deposition of chromogens utilizing pyrimidine analogs
摘要 ENHANCED DEPOSITION OF CHROMOGENS UTILIZING PYRIMIDINE 5OF THE DISCLOSURE This disclosure relates to compositions that enhance the deposition of detectable moieties on tissue samples, methods utilizing these compositions and kits including these compositions. The compositions include a deposition enhancer having a formula A-AA 10 R4' N R3 and/or S--R5) where R , R , R , and R4 are independently selected from aliphatic, aryl, halogen, a heteroatom-containing moiety, and hydrogen; R and/or R3 can be bound to R2 to 15 form a fused, aromatic ring system; R5 is selected from a heteroatom-containing moiety; A is selected from, a carbon atom, a heteroatom, other than sulfur, and any combination thereof; n is 1-5, an enzyme, a specific binding moiety and a detectable moiety.
申请公布号 AU2015207891(B2) 申请公布日期 2016.12.15
申请号 AU20150207891 申请日期 2015.07.30
申请人 Ventana Medical Systems, Inc. 发明人 May, Eric J.;Murillo, Adrian E.;Kosmeder, Jerome W.
分类号 C12Q1/68;G01N33/52;G01N33/531;G01N33/58 主分类号 C12Q1/68
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